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<\/a><\/p>\n<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\n<\/span><\/p>\nBibliography<\/strong><\/h5>\n1. Moore, Kathleen N, et al. \u201cNiraparib Monotherapy for Late-Line Treatment of Ovarian Cancer (Quadra): A Multicentre, Open-Label, Single-Arm, Phase 2 Trial.\u201d The Lancet Oncology, vol. 20, no. 5, 2019, pp. 636\u2013648.
2. Da Cunha Colombo Bonadio, Renata Rodrigues, et al. \u201cHomologous Recombination Deficiency in Ovarian Cancer: A Review of Its Epidemiology and Management.\u201d Clinics, 73(Suppl 1), 2018, p. e450s.
3. Watkins, Johnathan A et al. \u201cGenomic Scars As Biomarkers Of Homologous Recombination Deficiency And Drug Response In Breast And Ovarian Cancers\u201d. Breast Cancer Research, vol 16, no. 3, 2014.
4. Konstantinopoulos, Panagiotis A., et al. \u201cHomologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer.\u201d Cancer Discovery, vol. 5, no. 11, 2015, pp. 1137\u20131154.
5. Timms, Kirsten M, et al. \u201cComparison of Genomic Instability Test Scores Used for Predicting PARP Activity in Ovarian Cancer.\u201d Journal of Clinical Oncology, vol. 38, no. 15_suppl, 2020, pp. 1586\u20131586.
6. Baldwin, Rae L. et al. \u201cBRCA1 Promoter Region Hypermethylation in Ovarian Carcinoma: A Population-based Study.\u201d Cancer Research, vol. 60, no. 19, 2000, pp. 5329-5333.
Norquist, Barbara M. et al. \u201cInherited Mutations In Women With Ovarian Carcinoma\u201d. JAMA Oncology, vol 2, no. 4, 2016, p. 482.
7. The Cancer Genome Atlas Research Network. \u201cIntegrated Genomic Analyzes Of Ovarian Carcinoma\u201d. Nature, vol 474, no. 7353, 2011, pp. 609-615.
8. Weichert, W et al. \u201c216 An Evaluation Of The Performance Of Molecular Assays To Identify Homologous Recombination Deficiency-Positive Tumors In Ovarian Cancer\u201d. Late Breaking Abstracts, 2021.
9. Tew, William P., et al. \u201cPoly(ADP-Ribose) Polymerase Inhibitors in the Management of Ovarian Cancer: ASCO Guideline Rapid Recommendation Update.\u201d Journal of Clinical Oncology, vol. 40, no. 33, 2022, pp. 3878\u20133881.
10. Miller, Rowan E. et al. \u201cESMO Recommendations On Predictive Biomarker Testing For Homologous Recombination Deficiency And PARP Inhibitor Benefit In Ovarian Cancer\u201d. Annals Of Oncology, vol 31, no. 12, 2020, pp. 1606-1622.
11. Cristescu, Razvan et al. \u201c428 Genomic Instability Metric Concordance Between Oncoscan\u2122, Cytosnp And An FDA-Approved HRD Test\u201d. Translational Research, 2020.
12. National Comprehensive Cancer Network. Ovarian Cancer\/Fallopian Tube Cancer\/Primary Peritoneal Cancer. Version 1.2023.
13. https:\/\/info.foundationmedicine.com\/hubfs\/FMI%20Labels\/FoundationOne_CDx_Label_Technical_Info.pdf
14. Ray-Coquard, Isabelle, et al. \u201cOlaparib plus Bevacizumab First-Line Maintenance in Ovarian Cancer: Final Overall Survival Results from the Paola-1\/ENGOT-OV25 Trial.\u201d Annals of Oncology, vol. 34, no. 8, 2023, pp. 681\u2013692.
15. Ray-Coquard, Isabelle, et al. \u201cOlaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.\u201d New England Journal of Medicine, vol. 381, no. 25, 2019, pp. 2416\u20132428.
16. Gonz\u00e1lez-Mart\u00edn, Antonio, et al. \u201cNiraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.\u201d New England Journal of Medicine, vol. 381, no. 25, 2019, pp. 2391\u20132402.
17. Gonz\u00e1lez-Mart\u00edn, Antonio, et al. \u201cProgression-Free Survival and Safety at 3.5 Years of Follow-up: Results from the Randomized Phase 3 Prima\/Engot-OV26\/GOG-3012 Trial of Niraparib Maintenance Treatment in Patients with Newly Diagnosed Ovarian Cancer.\u201d European Journal of Cancer, vol. 189, 2023, p. 112908.
18. Coleman, Robert L., et al. \u201cVeliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer.\u201d New England Journal of Medicine, vol. 381, no. 25, 2019, pp. 2403\u20132415.
19. Denkert, Carsten, et al. \u201cHomologous Recombination Deficiency as an Ovarian Cancer Biomarker in a Real-World Cohort.\u201d The Journal of Molecular Diagnostics, vol. 24, no. 12, 2022, pp. 1254-1263.<\/h5>\n
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MyChoice\u00aeCDx PLUSHRD test on tumor tissueDetermination of homologous recombination deficiency (HRD) in ovarian cancer MyChoice CDx Plus is a genomic test that guides medical decisions in the treatment of ovarian cancer with PARP-inhibitors. The test is performed in the Myriad Genetics USA laboratories on a sample of ovarian tumor tissue. The search for [\u2026]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[13],"tags":[],"class_list":["post-51607","post","type-post","status-publish","format-standard","hentry","category-prodotti"],"yoast_head":"\n
MyChoice\u00aeCDx PLUS - eurobiodid - Oncologia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/quimark.com\/en\/mychoice\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MyChoice\u00aeCDx PLUS - eurobiodid - Oncologia\" \/>\n<meta property=\"og:description\" content=\"MyChoice\u00aeCDx PLUSTest HRD su tessuto tumoraleDeterminazione del deficit di ricombinazione omologa (HRD) nel tumore ovarico MyChoice CDx Plus \u00e8 un test genomico che guida le decisioni mediche nel trattamento del tumore ovarico con farmaci PARP-inibitori. Il test \u00e8 eseguito nei laboratori\u00a0Myriad Genetics USA su un campione di tessuto tumorale ovarico. 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