Multigene Germline Testing for Hereditary Cancer

MyRisk Plus Utilities

MyRisk is a multigene germline blood test that can help determine a patient's hereditary cancer risk by focusing on eleven of the most common hereditary cancers.

Which genes are tested?

Here are the 48 genes analyzed by MyRisk Plus. 

Predicting a disease

Genetic mutations passed down from parents can dramatically increase the risk of disease, including many types of cancer. In fact, patients with some rare inherited cancer syndromes may have up to a 100% chance of developing certain types of cancer.

The ongoing discovery of genes involved in cancer allows us to test for cancer-causing mutations in these genes, which may increase the risk of cancer.

Act consciously

If a patient has a mutation that puts them at increased risk for cancer, there are steps you can take to help reduce their risk through increased surveillance, chemoprevention, prophylactic surgery, and risk counseling.

Identifying your potential cancer risk is the first step in determining how best to delay, or even prevent, the development of certain cancers.

Who is MyRisk Plus for?

The MyRisk test is intended for both women and men.
If a patient has a personal or family history of cancer, hereditary cancer testing is the only way to determine whether that patient has a hereditary, familial, or general risk of developing future cancer.

Individuals with a familial or inherited risk of cancer are much more likely to develop cancer during their lifetime.

How do I use MyRisk Plus?

A blood sample is sent to Myriad Genetics laboratories in the USA where it is performed the MyRisk Plus test in a few days.   

The test must be requested by the attending physician, who will have access to the patient's report via the Myriad Genetics secure computing platform. 

The Report: MyRisk Plus provides clear and reliable results

The MyRisk Germline Test evaluates 48 genes linked to one or more of 11 tumor sites. Results will list the specific mutations found, including variants of uncertain significance (VUS). A summary of medical society guidelines is also provided to guide and optimize treatment decisions in MyRiskManagementTool (MMT).

Positive Result

High Result 

A high risk has been identified.

Understanding an elevated result

Negative Result

No clinically significant mutations.

Understanding a negative result

Variant of Uncertain Meaning
(Variant of Uncertain Significance( (VUS)

An undetermined risk mutation has been identified.

Technical Test Specifications (in English)

More information